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  • 產(chǎn)品名稱(chēng)： Deruxtecan
  • 產(chǎn)品貨號(hào)： CS00468
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購(gòu)： 3000
  • 數(shù)量：
    庫(kù)存： 10
  • 規(guī)格： 1mg
  • 產(chǎn)品信息
  • 如何訂購(gòu)
    產(chǎn)品描述
    Deruxtecan is an ADC drug-linker conjugate composed of a derivative of DX-8951 (DXd) and a maleimide-GGFG peptide linker, used for synthesizing DS-8201 and U3-1402. 
    靶點(diǎn)活性
    Camptothecins 
    體外活性
    Antibody-drug conjugates deliver anticancer agents selectively and efficiently to tumor tissue and have significant antitumor efficacy with a wide therapeutic window[2]. 
    別名
    化合物Deruxtecan 
    純度
    98%
    分子量
    1034.05 
    分子式
    C52H56FN9O13
    CAS No.
    1599440-13-7
    存儲(chǔ)
    Powder: -20°C for 3 years
    In solvent: -80°C for 2 years
    溶解度
    DMSO: 34 mg/mL (32.88 mM)
    H2O: < 0.1 mg/mL (insoluble)
    ( < 1 mg/ml refers to the product slightly soluble or insoluble )
    參考文獻(xiàn)
    1. NOGUCHI, Shigeru, et al. METHOD FOR SELECTIVELY MANUFACTURING ANTIBODY-DRUG CONJUGATE. WO2017002776A1.
    2. Ogitani Y, et al. Bystander killing effect of DS-8201a, a novel anti-human epidermal growth factor receptor 2 antibody-drug conjugate, in tumors with human epidermal growth factor receptor 2 heterogeneity. Cancer Sci. 2016 Jul;107(7):1039-46.
    Note
    For research use only .