瀏覽量: 165
- 產(chǎn)品名稱: Tocilizumab ELISA Kit
- 產(chǎn)品貨號(hào): CSKDC36901
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購(gòu): 6768
- 數(shù)量:
- 規(guī)格: 96T
- 產(chǎn)品信息
- 如何訂購(gòu)
Catalog No.
CSKDC36901
Stability and Storage
The stability of ELISA kit is determined by the loss rate of activity. The loss rate of this kit is less than 10% prior to the expiration date under appropriate storage condition.
Detection method
Colorimetric
Precision
CV<20%
Sample type
Plasma, Serum
Assay type
Quantitative
Sensitivity
0.156 μg/ml
Range
0.31-5 μg/mL
Recovery
80-120%
Specifications
Tocilizumab
Alternative Names
Atlizumab, MRA / R-1569 / RHPM-1 / RO-4877533, CAS: 375823-41-9
Background
Tocilizumab is a humanized IgG1 monoclonal antibody to the IL-6 receptor that is used largely as therapy of refractory rheumatoid arthritis and other inflammatory arthritides. Tocilizumab blocks the action of IL-6, which is a key proinflammatory cytokine that mediates a wide spectrum of biologic activities including activation of T cells, differentiation of B cells, induction of acute phase reactants, proliferation of fibroblasts, and damage to cartilage and joints. IL-6 levels are elevated in patients with active rheumatoid arthritis. In controlled trials and open label studies, tocilizumab therapy led to improvements in symptoms and laboratory abnormalities associated with several forms of inflammatory arthritis. Tocilizumab was approved for use in the United States in 2010 and current indications include rheumatoid arthritis, giant cell arteritis and both the polyarticular and systemic forms of juvenile idiopathic arthritis (formerly juvenile rheumatoid arthritis). Tocilizumab is considered a disease modifying antirheumatic drug (DMARD) and improves signs and symptoms of disease and decreases cartilage and tissue destruction.
Shipping
2-8 ℃
Note
For research use only .