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  • 產(chǎn)品名稱： c-Myc tag Peptide
  • 產(chǎn)品貨號： CSGP10151
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 441
  • 數(shù)量：
    庫存： 10
  • 規(guī)格： 5mg 25mg 10mM (in 1mL DMSO)
  • 產(chǎn)品信息
  • 如何訂購
    產(chǎn)品描述
    c-Myc Peptide is a useful displacement of c-Myc-tagged fusion proteins bound to anti-c-Myc antibodies in immunoassays. The successful inhibition of antibody binding by c-Myc peptide demonstrates binding is specific. c-Myc peptide participates in regulation of growth-related gene transcription.
    The c-Myc Peptide is a synthetic peptide with an amino acid sequence that corresponds to the amino acids 410-419 of the C-terminal of human c-myc. Myc (c-Myc) is a regulator gene that codes for a transcription factor. c-Myc activation results in numerous biological effects. The first to be discovered was its capability to drive cell proliferation (upregulates cyclins, downregulates p21), but it also plays a very important role in regulating cell growth (upregulates ribosomal RNA and proteins), apoptosis (downregulates Bcl-2), differentiation and stem cell self-renewal. C-Myc is a very strong proto-oncogene and it is very often found to be upregulated in many types of cancers. c-Myc overexpression stimulates gene amplification, [1] presumably through DNA over-replication.
    References:
    1. Denis N, Kitzis A, Kruh J, Dautry F, Corcos D (August 1991). "Stimulation of methotrexate resistance and dihydrofolate reductase gene amplification by c-myc". Oncogene 6 (8): 1453–7.
    Cas No.
    N/A 
    SDF
    N/A 
    別名
    H-Glu-Gln-Lys-Leu-Ile-Ser-Glu-Glu-Asp-Leu-OH 
    化學(xué)名
     c-Myc Peptide 
    Canonical SMILES
    N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H]([C@H](C)CC)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O 
    分子式
    C51H86N12O21
    分子量
    1203.3 
    溶解度
    ≥ 60.165mg/mL in DMSO, ≥ 15.7 mg/mL in H2O with ultrasonic
    儲存條件
    Desiccate at -20°C 
    General tips
    For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while. 
    Shipping Condition
    Evaluation sample solution : ship with blue ice
    All other available size: ship with RT , or blue ice upon request 
    Purity
    >98.00%
    Note
    For research use only .