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  • 產(chǎn)品名稱： β-Sheet Breaker Peptide iAβ5
  • 產(chǎn)品貨號： CS-P1047
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 1100
  • 數(shù)量：
    庫存： 5
  • 規(guī)格： 10mg
  • 產(chǎn)品信息
  • 如何訂購
    生物活性
    β-Sheet Breaker Peptide iAβ5 is a potent degrader of cerebral amyloid-beta (Abeta). Abeta deposition is associatied with the Alzheimer disease (AD), due to its related toxicity linked to its beta-sheet conformation and/or aggregation. β-Sheet Breaker Peptide iAβ5 reproducibly induces in vivo disassembly of fibrillar amyloid deposits. Thus, β-Sheet Breaker Peptide iAβ5 prevents and/or reverses neuronal shrinkage caused by Abeta, and reduces the extent of interleukin-1beta positive microglia-like cells that surround the Abeta deposits. β-Sheet Breaker Peptide iAβ5 reduces the size and/or number of cerebral amyloid plaques in AD. β-Sheet Breaker Peptide iAβ5 labeled by hydrophobic benzyl alcohol (HBA) tag, can be used for quantitative assay by showing vivid blue color under acidic conditions.
    分子量
    637.72
    性狀
    固體
    Formula
    C33H43N5O8
    CAS 號
    182912-74-9
    Sequence
    Leu-Pro-Phe-Phe-Asp
    Sequence Shortening
    LPFFD
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    運輸條件
    Room temperature in continental US; may vary elsewhere.
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    儲存方式
    Sealed storage, away from moisture and light, under nitrogen
    Powder -80°C 2 years;-20°C 1 year
    *In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light, under 
    純度
    99.92%
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    Note
    For research use only .