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  • 產(chǎn)品名稱： Research Grade Cetuximab ( 西妥昔單抗 )
  • 產(chǎn)品貨號： CSD00079
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 2480
  • 數(shù)量：
    庫存： 100
  • 規(guī)格： 100μg
  • 產(chǎn)品信息
  • 如何訂購
    貨號（Catalog No.）
    CSD00079
    通用名INN
    Cetuximab
    純度(Purity)
    >95%
    濃度( Concentration)
    1mg/ml
    Formulation
    PBS buffer PH7.5
    Source
    CHO cells
    內(nèi)毒素(Endotoxin level)
    Please contact with the lab for this information.
    產(chǎn)品描述(Description)
    Cetuximab is an epidermal growth factor receptor binding FAB.Cetuximab is composed of the Fv (variable; antigen-binding) regions of the 225 murine EGFr monoclonal antibody specific for the N-terminal portion of human EGFr with human IgG1 heavy and kappa light chain constant (framework) regions.Cetuximab is marketed under the brand Erbitux by Eli Lilly and Company.In the United States,a regimen of cetuximab costs approximately $30,790 for an eight-week course.Cetuximab binds to the epidermal growth factor receptor (EGFr) on both normal and tumor cells. EGFr is over-expressed in many colorectal cancers.Cetuximab competitively inhibits the binding of epidermal growth factor (EGF) and TGF alpha,thereby reducing their effects on cell growth and metastatic spread.
    別名(Alternative names)
    Fab C225,IMC-225
    靶點;物種(Specificity target name;species)
    EGFR[Homo sapiens]
    種類(Species)
    Chimeric
    受體鑒定(Receptor identification)
    IgG1-kappa
    分子量(MV)
    145781.6 Da
    CAS
    205923-56-4
    存儲條件(Storage)
    Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
    Store at +4°C short term (1-2 weeks).
    Store at -20 °C 12 months.
    Store at -80°C long term.
    Note
    For research use only .