瀏覽量: 102
- 產(chǎn)品名稱: Research Grade Raxibacumab ( 雷昔庫單抗 )
- 產(chǎn)品貨號(hào): CSD00167
- 貨期: 現(xiàn)貨
- 價(jià)格與訂購: 2480
- 數(shù)量:
- 規(guī)格: 100μg
- 產(chǎn)品信息
- 如何訂購
貨號(hào)(Catalog No.)
CSD00167
通用名INN
Raxibacumab
純度(Purity)
>95%
濃度( Concentration)
1mg/ml
Formulation
PBS buffer PH7.5
Source
CHO cells
內(nèi)毒素(Endotoxin level)
Please contact with the lab for this information.
產(chǎn)品描述(Description)
Raxibacumab is a human IgG1λ monoclonal antibody that binds the protective antigen (PA) component of B. anthracis toxin. Raxibacumab has a molecular weight of approximately 146 kilodaltons. Raxibacumab is produced by recombinant DNA technology in a murine cell expression system. FDA approved on December 14, 2012.
別名(Alternative names)
IDEC-C2B8
靶點(diǎn);物種(Specificity target name;species)
Anthrax protective antigen [Bacillus anthracis]
活性研究(體外/體內(nèi)研究)(Activity in vitro)
In vitro, PA-824 exhibits the high activity against multidrug-resistant clinical isolates from Asia (India and South Korea) and from throughout the United States (MIC <1 μg/ml) and is equally active against the drug-sensitive and multidrug-resistant isolates of M. tuberculosis (MICs range, 0.039 to 0.531 μg/ml). A recent study shows that single-nucleotide polymorphisms of PA-824 resistance genes (fgd1 [Rv0407] and ddn [Rv3547]) don't significantly affect the PA-824 MICs (≤ 0.25 μg/ml).
種類(Species)
Homo sapiens
受體鑒定(Receptor identification)
IgG1-lambda
分子量(MV)
142844.53 Da
CAS
565451-13-0
存儲(chǔ)條件(Storage)
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Store at +4°C short term (1-2 weeks).
Store at -20 °C 12 months.
Store at -80°C long term.
Note
For research use only .