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- 產(chǎn)品名稱： Recombinant Human CD147 protein
- 產(chǎn)品貨號(hào)： CSP00046
- 貨期： 現(xiàn)貨
- 價(jià)格與訂購： 2880
- 數(shù)量：
庫存： 100
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- 產(chǎn)品信息
- 如何訂購
產(chǎn)品名（Product Name）
Recombinant Human CD147 protein
貨號(hào)（Catalog No.）
CSP00046
描述（description）
Recombinant Human CD147 is produced by E.coli expression system and the target gene encoding Ala22-Ala207 is expressed with His Tag
表達(dá)系統(tǒng)（Expression system）
E.coli
種屬（Species）
Homo sapiens (Human)
Accession #
P35613
別名（Alternative names)
5F7 Protein, Human; Basigin Protein, Human; CD147 Protein, Human; EMMPRIN Protein, Human; M6 Protein, Human; OK Protein, Human; TCSF Protein, Human
預(yù)測分子量（Predicted Molecular Mass）
22.59 kDa
純度（Purity）
>90% as determined by SDS-PAGE
內(nèi)毒素（Endotoxin level）
Please contact with the lab for this information
制劑（Formulation）
Supplied as solution form in PBS, pH7.5 or lyophilized from PBS, pH7.5
運(yùn)輸方式（Shipping）
In general, proteins are shipped out with blue ice unless customers require otherwise.
穩(wěn)定性&儲(chǔ)存（Stability &Storage）
Use a manual defrost freezer and avoid repeated freeze thaw cycles.
Store at 2 to 8 °C for one week .
Store at -20 to -80 °C for twelve months from the date of receipt.
復(fù)溶（Reconstitution）
Please refer to the instraction in the hard copy of COA.
應(yīng)用（Application）
Immunogen
背景（Background）
CD147/EMMPRIN (Extracellular Matrix Metalloproteinase Inducer), also known as Basigin (BSG), is a transmembrane glycoprotein with different forms resulted from different modes of glycosylation and N-terminal sequence variants. It is a member of the immunoglobulin superfamily with homology to both the immunoglobulin V domain and MHC class II antigen beta-chain. This protein play important roles in variety of events including spermatogenesis, embryo implantation, neural network formation. CD147 induces the production and release of matrix metalloproteinases (MMP) in the surrounding mesenchymal cells and tumor cells, and thereby promotes invasion, metastasis, growth and survival of malignant cells. Furthermore, CD147 also serves as a receptor for extracellular cyclophilinthe and its association with integrins might be important in signal transduction. Recently, CD147 displays increased expression in many cancers, and it has been previously demonstrated to participate in cancer metastasis and progression. Thus, CD147 and its antibody are used as an effective treatment for malignant cancers.
icon Note
For research use only .
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