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  • 產(chǎn)品名稱： Anti SARS-CoV-2(2019-nCoV) S protein RBD monoclonal antibody(F3C10)
  • 產(chǎn)品貨號(hào)： CSMA10313Mo
  • 貨期： 現(xiàn)貨
  • 價(jià)格與訂購： 2880
  • 數(shù)量：
    庫存： 100
  • 規(guī)格：
  • 產(chǎn)品信息
  • 如何訂購
    產(chǎn)品名（Product Name）
    Anti SARS-CoV-2(2019-nCoV) S protein RBD monoclonal antibody(F3C10)
    貨號(hào)（Catalog No.）
    CSMA10313Mo
    描述（description）
    This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant SARS-CoV-2(2019-nCoV) RBD protein.
    特異性（Spcificty）
    Recognizes SARS-CoV-2 S Protein RBD
    亞型（Isotype）
    IgG 1
    克隆性（Clonality）
    Monoclonal
    克隆號(hào)（Clone No.）
    F3C10
    別名（Alternative names)
    S glycoprotein,E2,Peplomer protein,Spike protein S1
    Accession #
    P0DTC2
    宿主（Host）
    Mouse
    背景（Background）
    Protein S (PROS1) is glycoprotein and expressed in many cell types supporting its reported involvement in multiple biological processes that include coagulation, apoptosis, cancer development and progression, and the innate immune response. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2, DPP4, CEACAM etc.. The spike (S) glycoprotein of coronaviruses is known to be essential in the binding of the virus to the host cell at the advent of the infection process. Most notable is severe acute respiratory syndrome (SARS). The severe acute respiratory syndrome-coronavirus (SARS-CoV) spike (S) glycoprotein alone can mediate the membrane fusion required for virus entry and cell fusion. It is also a major immunogen and a target for entry inhibitors. It's been reported that 2019-nCoV can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.
    濃度（Concentration）
    0.98mg/ml
    分子量（MW）
    142kDa
    偶連物（Conjugation）
    Unconjugate
    種屬反應(yīng)性（Species reactivity）
    Severe acute respiratory syndrome coronavirus 2 (2019-nCoV) (SARS-CoV-2)
    應(yīng)用實(shí)驗(yàn)（Tested applications）
    WB;ELISA;ICC.
    免疫原（Immunogen）
    Recombinant SARS-CoV-2 S Protein RBD
    icon
    狀態(tài)（Form）
    Liquid
    穩(wěn)定性&儲(chǔ)存（Stability &Storage）
    Use a manual defrost freezer and avoid repeated freeze thaw cycles.
    Store at 2 to 8 °C for one week .
    Store at -20 to -80 °C for twelve months from the date of receipt.
    儲(chǔ)存溶液（Buffer）
    PBS, pH7.4, containing 0.05% proclin300, 50% glycerol.
    應(yīng)用實(shí)驗(yàn)及稀釋比例（Dilution Range）
    WB:1:1000 - 1:3000;ELISA:1:1000-1:3000;ICC:1:1000.
    Note
    For research use only .