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  • 產(chǎn)品名稱： Sulfo-SMCC sodium
  • 產(chǎn)品貨號： CST18728
  • 貨期： 現(xiàn)貨
  • 價格與訂購： 417
  • 數(shù)量：
    庫存： 5
  • 規(guī)格： 10 mg
  • 產(chǎn)品信息
  • 如何訂購
    產(chǎn)品名（Product Name）
    Sulfo-SMCC sodium
    貨號（Catalog No.）
    CST18728
    產(chǎn)品描述
    Sulfo-SMCC sodium is a commonly used hetero-bifunctional, non-cleavable ADC crosslinker bearing N-hydroxysuccinimide (NHS) ester and maleimide groups to react with primary amines and sulfhydryl groups, respectively.

    The crosslinker Sulfo-SMCC consists of a maleimide and an N-hydroxysuccinimide ester group to bind to sulfhydryl groups and primary amines, respectively. Sulfo-SMCC inhibits the end-to-end annealing of stabilized Microtubules (MTs). MTs are treated with 250 μM Sulfo-SMCC, and imaged after incubation for 0 h, 6 h, and 24 h. MTs treated with Sulfo-SMCC shows a constant mean length, independent of the incubation time[1].
    分子式
    C16H17N2NaO9S
    分子量
    436.37
    參考文獻(xiàn)
    [1]Prabhune M, et al. Sulfo-SMCC Prevents Annealing of Taxol-Stabilized Microtubules In Vitro. PLoS One. 2016 Aug 25;11(8):e0161623.
    儲存和溶解度
    H2O:12 mg/mL (27.50 mM),Need ultrasonic
    DMSO:125 mg/mL (286.45 mM),Need ultrasonic
    Powder: -20°C for 3 years
    In solvent: -80°C for 2 years                                                                                                                                                                                                                                                                      
    Note
    For research use only .