瀏覽量: 115
- 產(chǎn)品名稱: Pirlindole 坡爾吲哚
- 產(chǎn)品貨號: CSGC41251
- 貨期: 現(xiàn)貨
- 價格與訂購: 850
- 數(shù)量:
- 規(guī)格: 5mg
- 產(chǎn)品信息
- 如何訂購
產(chǎn)品名稱
Pirlindole
產(chǎn)品描述
Pirlindole is a selective and reversible monoamine oxidase A (MAO-A) inhibitor (IC50s = 250 and 34.2 nM for rat brain and heart MAO-A, respectively). It is selective for MAO-A over MAO-B (Kis = 52,100 and 59,900 nM, for rat brain and heart MAO-B, respectively). In rats, it reverses the depressive-like effects induced by chronic mild stress (CMS), increases proliferation of hippocampal neural progenitor cells, and reverses dendritic atrophy in granule neurons. Pirlindole is also an inhibitor of enterovirus-D68 and coxsackievirus B3 (CV-B3), inhibiting the genome replication phase of CV-B3 infection with an EC50 value of 7.7 μM independent of MAO-A activity.
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CAS N0.
60762-57-4
別名
坡爾吲哚
Purity
>98%
Canonical SMILES
CC1=CC=C(N2C3=C4CCCC3NCC2)C4=C1
分子式
C15H18N2
分子量
226.3
溶解度
con
con
DMF: 1 mg/ml,DMSO: 5 mg/ml
儲存條件
Store at -20°C
General tips
For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.
Shipping Condition
Evaluation sample solution : ship with blue ice
All other available size: ship with RT , or blue ice upon request
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All other available size: ship with RT , or blue ice upon request
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Note
For research use only .